Potential antiatherosclerotic agents. 5. An acyl-CoA:cholesterol O-acyltransferase inhibitor with hypocholesterolemic activity

J Med Chem. 1986 Jul;29(7):1131-3. doi: 10.1021/jm00157a002.
No abstract available

MeSH terms

  • Animals
  • Anticholesteremic Agents / chemical synthesis*
  • Arteriosclerosis / drug therapy*
  • Cells, Cultured
  • Cholesterol / metabolism
  • Cholesterol, LDL / metabolism
  • Haplorhini
  • Humans
  • Intestinal Absorption / drug effects
  • Liver / metabolism
  • Muscle, Smooth, Vascular / enzymology
  • Phenylurea Compounds / chemical synthesis*
  • Phenylurea Compounds / pharmacology
  • Phenylurea Compounds / therapeutic use
  • Sterol O-Acyltransferase / antagonists & inhibitors*

Substances

  • Anticholesteremic Agents
  • Cholesterol, LDL
  • Phenylurea Compounds
  • CL 277082
  • Cholesterol
  • Sterol O-Acyltransferase